Download torrent Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet

Download torrent Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet

Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet.cChakraborty Pranabesh
Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet
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Author: Chakraborty Pranabesh
Number of Pages: 64 pages
Published Date: 07 Nov 2013
Publisher: LAP Lambert Academic Publishing
Publication Country: United States
Language: English
ISBN: 9783659374005
File size: 44 Mb
File Name: Mucoadhesive.Formulation.and.Evaluation.of.Terbutaline.Sulphate.Tablet.pdf
Download Link: Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet
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Bioadhesive polymers that bind to the gastric mucin or epithelial cell surface are useful in drug delivery for the purpose of (a) retaining a dosage form in the G.I tract and (b) increasing the intimacy and duration of contact of drug with the absorbing membrane. In this investigation, natural mucoadhesive materials were isolated from different edible fruits like Aegle marmelos (Linn.) Cor., Zizyphus mauritiana and Tamarindus indica by hot extraction method. Density and swelling property of natural materials were evaluated. Bioadhesive and mucoadhesive qualities of natural materials were evaluated individually by different in vitro testing methods and in vivo X-ray photograph method. It was observed that natural materials have good mucoadhesive property. Mucoadhesive tablets containing 7.5 mg of terbutaline sulphate tablets were prepared by wet granulation method. The sustained release pattern was evaluated by in vitro and in vivo studies. The drug release data were plotted using various kinetic equations (zero order, first order, Higuchi's kinetics.Finally we confirmed our investigation by invitro-invivo correlation study.

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